The Holy Grail of Finding an HIV Cure

Many in the scientific and medical communities are happy with the significant progress already made in treatment methods such as antiretroviral therapy, but think there is more that can be done. It is the topic of a recent article signed by Dr. Alain Lafeuillade, MD, PhD, chair of the 5th International Workshop on HIV Persistence: "Potential Strategies for an HIV Infection Cure". HIV Clinical Trials 2011; 12 (3):121-30

Online PR News – 18-June-2011 –When it comes to HIV, any talk of a "cure" is spoken of with extreme trepidation. It's been elusive for years now, and while there have been many advances in HIV treatment, an outright cure for the disease seems like it's far in the distant future, if it'll ever be found at all. Should HIV be treated as a chronic disease with life-long treatment and leave it at that, or should more be done about finding a cure for HIV? Many in the scientific and medical communities are happy with the significant progress already made by antiretroviral therapy, but think there is more that can be done: HIV curative strategies are the next step. This is the topic of a recent article signed by Dr. Alain Lafeuillade, MD, PhD, chair of the 5th International Workshop on HIV Persistence: "Potential Strategies for an HIV Infection Cure". HIV Clinical Trials 2011; 12 (3):121-30. DOI10.1310/hct1203-121

"This article is kind of a roadmap to grab the holy grail of an HIV Cure"

This article is kind of a roadmap to grab the holy grail of an HIV Cure

There are currently two ways being explored to find a cure for HIV. First is finding a functional cure, where the virus is completely suppressed and no further treatment is necessary. The second way is a sterilizing cure, where the virus is rendered unable to replicate and eliminated from the body altogether. Either one would be a major victory in the battle to eradicate the worldwide HIV epidemic. However, HIV is persistent. It lies dormant in what are called HIV reservoirs, and once HIV treatment ceases, the reservoirs release the HIV inside them and they start replicating freely. Furthermore, the virus can lie dormant in CD4 cells. So, even seemingly healthy people aren't free of the virus; the virus is still inside them, waiting for the right time to replicate again.
The Berlin Patient, the famous HIV patient who emerged cured of HIV after a bone marrow transplant from a person with a rare genetic disorder that made them resistant to HIV infection, gives hope that some type of cure can be found in the very near future. The technology is there, as is the science. It's just a matter of putting the right pieces in the right places, and coming up with the right formula to finally grab the holy grail of an HIV cure.

About the article:
http://thomasland.metapress.com/content/x8881t532t6l/?p=658cdce88a2646b2bb3ffd35af2526b2&pi=0

About the 5th International Workshop on HIV Persistence:
http://www.informedhorizons.com/persistence2011/

Contact:
Dr. Alain Lafeuillade, MD, PhD, Department of Infectious Diseases, General Hospital, 1208 Avenue Colonel Picot, 83056 Toulon, France, Email: alain.lafeuillade@ch-toulon.fr

 
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