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Histomorphometry shows decreased bone turnover with balanced bone formation and resorption during hibernation. The purpose of hibernation is to conserve metabol

Online PR News – 15-November-2017 – MD – Histomorphometry shows decreased bone turnover with balanced bone formation and resorption during hibernation. The purpose of hibernation is to conserve metabolic energy Obeticholic Acid price when food is unavailable. Fat is the primary energy source during hibernation; bears lose 30-40% of their body mass (almost exclusively fat mass) during hibernation. Bears also experience markedly decreased kidney function and do not urinate or defecate during hibernation, but maintain eucalcemia. The purpose of this study was to quantify seasonal bear serum markers of bone formation (BSAP) and osteoclast number (TRAP), which do not accumulate with decreased kidney function. To assess bone/fat/energy relationships, we also quantified serum osteocalcin (OC), adiponectin, NPY, insulin, and glucose. Serum was collected every 10 days from black bears before, during, and after hibernation. Serum BSAP and TRAP decreased (p

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Bettino Sims
Horatio
96 Yukon
73 Saskatchewan LA, 38722

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