New Publication: WoundShield Ultrasound Increases Oxygen Delivery to Lower Extremity Wounds

WoundShield ultrasound together with hyper-oxygenated saline increase oxygen levels in lower extremity wounds. Increased oxygen level has proved to promote angiogenesis, promote collagen formation, and fibroblast production.

Online PR News – 11-September-2012 – Nesher/ Israel – Nesher, Israel - NanoVibronix, a medical device company which develops innovative therapeutic ultrasound applications, reported that a study titled "Ultrasound-Mediated Oxygen Delivery to Lower Extremity Wounds" has been published in Wounds journal by Scott Covington MD; George L. Adams, MD and Krys Dixon, WOCN, RN from Duke Raleigh Wound Clinic; University of North Carolina, School of Medicine and Duke/Raleigh Hospital, Raleigh, NC.

This case series investigated the effects of oxygen therapy delivery augmented by low-frequency ultrasound with hyper-oxygenated saline to deliver oxygen to wounds. Partial Oxygen levels were measured, in 7 patients with CLI (Critical Limb Ischemia) and full-thickness wounds, before (baseline), after provision of hyper-oxygenated saline, and after sonification.

The WoundShield device was found to successfully oxygenate the wound beds; PaO2 levels increased by a median of 59.7%, a maximum of 116%, and a median absolute difference peaking at 0.8 mmHg PaO2 (P = 0.018).

WoundShield portable ultrasound provides an excellent tool to help increase oxygen levels at the wound bed

"Surface Acoustic Waveform (SAW) technology facilitates the delivery of the dissolved gas at a depth in the wound bed. Increased oxygen level has proved to be physiologically effective in promoting angiogenesis, promoting collagen formation, and fibroblast production," says Dr. Covington. "If this can be achieved clinically, dissolved oxygenation procedures may complement systemic methods of oxygenation (hyperbaric) and may also allow for greater therapeutic versatility in treating wounds, possibly in a homecare environment for patients not clinically indicated for HBO," he added.

"Low-frequency sonophoresis has been well documented to enhance the permeability of skin to drugs and creams," says Amir Rippel, Vice President of Marketing at NanoVibronix. "The WoundShield portable ultrasound provides an excellent tool to help increase oxygen levels at the wound bed for expedited wounds healing at the homecare environment adjunctively or as an alternative to the HBOT (Hyperbaric Oxygen Therapy) where it may not be clinically indicated."

The WoundShield carries the CE Mark certification.

About NanoVibronix
Located in Farmingdale, New York with a subsidiary in Nesher Israel, NanoVibronix develops medical devices that implement its proprietary therapeutic ultrasound technology. The company is expanding its portable, therapeutic platform to wounds care targeting expedited healing of chronic and acute wounds. NanoVibronix has also developed and markets the PainShield intended to treat pain and recover soft tissue injury and the UroShield catheter-based disposable ultrasound intended to reduce pain and discomfort and help prevent UTI in indwelling urinary catheters.

Contact Information
Amir Rippel
NanoVibronix Ltd.

+972-4-820 0581

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